Gene name:
    LTB4R (BLT;BLT1;BLTR;CMKRL1;GPR16;P2RY7) ;
    
 
    Protein name:
    Leukotriene B4 receptor 1 (LTB4-R 1;LTB4-R1) ;
    
    Alternative:
    
    G-protein coupled receptor 16 ;Chemoattractant receptor-like 1 ;P2Y purinoceptor 7 (P2Y7) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Function:
    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Cell membrane  
      Multi-pass membrane protein 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MNTTSSAAPP |  SLGVEFISLL |  AIILLSVALA |  VGLPGNSFVV |  WSILKRMQKR |  
    
 
    100:
    SVTALMVLNL |  ALADLAVLLT |  APFFLHFLAQ |  GTWSFGLAGC |  RLCHYVCGVS |  
    
 
    150:
    MYASVLLITA |  MSLDRSLAVA |  RPFVSQKLRT |  KAMARRVLAG |  IWVLSFLLAT |  
    
 
    200:
    PVLAYRTVVP |  WKTNMSLCFP |  RYPSEGHRAF |  HLIFEAVTGF |  LLPFLAVVAS |  
    
 
    250:
    YSDIGRRLQA |  RRFRRSRRTG |  RLVVLIILTF |  AAFWLPYHVV |  NLAEAGRALA |  
    
 
    300:
    GQAAGLGLVG |  KRLSLARNVL |  IALAFLSSSV |  NPVLYACAGG |  GLLRSAGVGF |  
    
 
    350:
    VAKLLEGTGS |  EASSTRRGGS |  LGQTARSGPA |  ALEPGPSESL |  TASSPLKLNE |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Human
         
        
        Mouse
         
        
        Bovine
         
        
        Rat
         
        
     
    
        ELISA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human LTB4-R 1
        
     
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human LTB4-R 1
        
     
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human LTB4-R 1
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                        
                            "Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells." 
                        
                        
                            Akbar G.K.M. 
                        ,
                            
Dasari V.R. 
                        ,
                            
Webb T. 
                        ,
                            
Ayyanathan K. 
                        ,
                            
Pillarisetti K. 
                        ,
                            
Sandhu A.K. 
                        ,
                            
Athwal R.S. 
                        ,
                            
Daniel J.L. 
                        ,
                            
Ashby B. 
                        ,
                            
Barnard E.A. 
                        ,
                            
Kunapuli S.P. 
                        
                        
                        
                        
                            J. Biol. Chem.271:18363-18367(1996)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                 
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                 
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                6.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                        
                            "Cloning of human full-length CDSs in BD Creator(TM) system donor vector." 
                        
                        
                            Kalnine N. 
                        ,
                            
Chen X. 
                        ,
                            
Rolfs A. 
                        ,
                            
Halleck A. 
                        ,
                            
Hines L. 
                        ,
                            
Eisenstein S. 
                        ,
                            
Koundinya M. 
                        ,
                            
Raphael J. 
                        ,
                            
Moreira D. 
                        ,
                            
Kelley T. 
                        ,
                            
LaBaer J. 
                        ,
                            
Lin Y. 
                        ,
                            
Phelan M. 
                        ,
                            
Farmer A. 
                        
                        
                        
                            Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346 
                    
                    
                 
             
         
            
        
            
                8.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346 
                    
                    
                    tissue :
                    
Lung .  
             
         
            
        
            
                9.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for PHOSPHORYLATION;MUTAGENESIS OF THR-308 AND SER-310